Neuroblastoma is a cancer disease that occurs from immature nerve cells found in many parts of the body.
Neuroblastoma most popularly happens in and around the adrenal glands, which have similar origins to nerve cells and sit atop the kidneys. However, neuroblastoma can also promote in other parts of the abdomen and in the chest, neck, and near the spine, where groups of nerve cells exist. Neuroblastoma most popularly influences children age five or younger, though it may often happen in older children. Some forms of neuroblastoma cancer go away on their own, while others may need multiple treatments. The child’s neuroblastoma treatment choices will be based on many factors.
Symptoms of Neuroblastoma Cancer
Signs and symptoms of neuroblastoma cancer differ based on what area of the body is affected. Neuroblastoma in the abdomen and in the chest, the most prevalent form may make signs and symptoms like
1) Lumps of tissue under the skin
2) Dark circles around the eyes
3) Back pain
5) Unexplained weight loss
6) Bone pain
Neuroblastoma Cancer Causes
In general, cancer starts with a genetic mutation that permits normal, healthy cells to continue increasing without answering to the signals to stop, which healthy cells do. Cancer cells grow and multiply out of control. The accumulating abnormal cells shape a tumor. Causes of Neuroblastoma cancer starts in neuroblasts immature nerve cells that a fetus creates as part of its development process.
As the fetus matures, neuroblasts ultimately turn into nerve cells and fibers and the cells that make up the adrenal glands. Most neuroblasts evolve by birth, though a small number of immature neuroblasts can be found in a newborn baby. In most cases, these neuroblasts mature or go away. Others, however, form tumor neuroblastoma. It is not clear what causes Neuroblastoma cancer, the primary genetic mutation that generates neuroblastoma.
Complications of Neuroblastoma Cancer
Complications of neuroblastoma cancer may contain:
1) Spread of cancer: Neuroblastoma may expand to other areas of the body, like the lymph nodes, bone marrow, liver, skin, and bones.
2) Spinal cord compression: Tumors may increase and press on the spinal cord, making spinal cord compression. Spinal cord compression may produce pain and paralysis.
3) Signs and symptoms caused by tumor secretions: Neuroblastoma cells may secrete specific chemicals that irritate other healthy tissues, making signs and symptoms known as paraneoplastic syndromes. One paraneoplastic syndrome that rarely happens in people with neuroblastoma causes rapid eye movements and complexity with coordination. Another rare syndrome makes abdominal swelling and diarrhea. These three are the complications of neuroblastoma cancer.
Diagnosis of Neuroblastoma Cancer
Tests and procedures used for the diagnosis of neuroblastoma cancer consist of:
1) Physical test
2) Urine and blood examine
3) Imaging test
4) Removing a tissue sample for testing
5) Removing a bone marrow sample for testing
Neuroblastoma Cancer Treatments
The child’s doctor prefers a treatment plan depend on many factors that influence the child’s prognosis. Factors include the child’s age, the stage of cancer, the type of cells involved in cancer, and whether there are any irregularities in the chromosomes and genes.
The child’s doctor applies this information to categorize cancer as low risk, intermediate-risk, or high risk. What Neuroblastoma treatment or combination of treatments your child gets for neuroblastoma based on the risk category. Other treatments of Neuroblastoma cancer may include the following:
3) Radiation Therapy
4) Bone marrow transplant