Multiple sclerosis (MS) is a terrible disabling disease of the brain and spinal cord, which is our central nervous system.
In MS, the immune system attacks the protective sheath (myelin) that protects nerve fibers and makes communication problems between your brain and the rest of your body. Eventually, the disease can cause permanent injury or deterioration of the nerves.
Signs and symptoms of MS differ widely and depend on the amount of nerve injury and which nerves are affected. Some people with chronic MS may lose the potential to walk independently or at all, while others may feel long periods of remission without any new symptoms.
What are the symptoms of Multiple Sclerosis?
Multiple sclerosis signs and symptoms may vary significantly from person to person, and throughout the disease depends on the location of affected nerve fibers. Symptoms sometimes affect movement, like
1) Numbness or weakness in one or more limbs that typically happens on one side of your body at a time, or the legs and trunk
2) Electric-shock sensations that occur with precise neck movements, especially bending the neck forward
3) Tremor or unsteady gait
Vision problems are also common in this disease like
1) Partial or complete vision loss, generally in one eye at a time, sometimes with pain during eye movement
2) Prolong double vision
3) Blurry vision
Some other multiple sclerosis symptoms include
1) Slurred speech
4) Experience pain in some parts of your body
5) Problems with sexual and bladder function
What is the Multiple Sclerosis disease course?
Most of the people with MS have a relapsing-remitting disease course. They feel periods of new symptoms or relapses that progress over days or weeks and generally develop partially or entirely. These relapses are followed by quiet periods of disease remission that can stay last months or even years.
Small rises in body temperature can temporarily worsen the signs and symptoms of MS, but these are not considered disease relapses.
About 60 to 70 percent of people with relapsing-remitting MS eventually build up a steady progression of symptoms, with or without periods of remission, called secondary-progressive MS.
The worsening of symptoms generally includes problems with mobility and gait. The rate of disease progression differs significantly among people with secondary-progressive MS.
Some people with MS experience a gradual onset and steady progression of signs and symptoms without any relapses. This is called primary-progressive MS.
What are the causes of Multiple Sclerosis?
The cause of multiple sclerosis is unknown. It is considered an autoimmune disease in which the immune system of the body triggers its own tissues. In the case of MS, this immune system malfunction smashed the fatty substance that coats and covers nerve fibers in the brain and spinal cord.
The spinal cord is compared to the insulation coating on electrical wires. When the protective spinal cord is injured, and nerve fiber is exposed, the messages that go along that nerve may be slowed or blocked. The nerve may also become damaged.
It is not clear why MS progress in some people and not others. A combination of genetics and environmental factors comes to be responsible.
What are the risk factors related to Multiple Sclerosis?
1) Age:Â MS can happen at any age, but generally attacks people somewhere between the ages of 16 and 55.
2) Sex:Â Women are more than two to three times more as unlike men are to have relapsing-remitting MS.
3) Family history:Â If one of your parents or siblings has MS, you are at a higher risk of suffering the disease.
4) Certain infections: A variety of viruses have been connected to MS, including Epstein-Barr, the virus that causes infectious mononucleosis.
5) Race:Â White people, particularly those of the Northern European region, are at the highest risk of promoting MS. People of Asian, African, or Native American areas have the lowest chance.
6) Climate: MS is far more common in countries with climate changes, including Canada, the northern United States, New Zealand, southeastern Australia, and Europe.
7) Vitamin D: Having low levels of vitamin D and little exposure to sunlight is related to a higher risk of MS.
What are the complications generally seen in Sclerosis?Â
People are suffering from multiple sclerosis may also promote
1) Stiffness of muscle
2) Paralysis typically occurs in the legs
3) Bladder problems or sexual function
4) Mental changes such as forgetfulness or mood swings